Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

947
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
947
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.4K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute Macular Neuroretinopathy and Peripheral Retinal Abnormalities in a Patient With Adams-Oliver Syndrome.

Journal of vitreoretinal diseases·2026
Same author

Bilateral Giant Pigment Epithelial Detachments and Unilateral RPE Tear and Exudative Retinal Detachment After Tadalafil Exposure: Case Report and Review of the Literature.

Retinal cases & brief reports·2026
Same author

Neuroprotective Agents for Photoreceptor Rescue Following Experimental Retinal Detachment in Rodents: A Systematic Review.

Investigative ophthalmology & visual science·2026
Same author

Influence of Anti-VEGF Injections on Longitudinal Changes in Vascular Metrics Measured by OCTA in Age Related Macular Degeneration: A Retrospective Real-World Study.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Ocular Lymphatics in Health and Disease.

Diagnostics (Basel, Switzerland)·2026
Same author

Outcomes and Complications of Secondary Intraocular Lens Implantation: Insights From a Vitreoretinal Surgery Cohort.

Ophthalmic surgery, lasers & imaging retina·2026
Same journal

Presumed Bilateral Retinitis Associated with JC Virus in a Patient with HIV AIDS.

Ocular immunology and inflammation·2026
Same journal

Safety and Efficacy of Adalimumab in the Treatment of Refractory Behçet's Uveitis: A Prospective Cohort Study.

Ocular immunology and inflammation·2026
Same journal

Role of Adjunctive Intravitreal Therapy in Intraocular Tubercular Granuloma at a Tertiary Uveitis Care Centre - A Retrospective Case Series.

Ocular immunology and inflammation·2026
Same journal

Sex Differences in Uveitis Etiology: A Systematic Review and Meta-Analysis.

Ocular immunology and inflammation·2026
Same journal

Upadacitinib in Refractory Vogt-Koyanagi-Harada Disease: A Case Report.

Ocular immunology and inflammation·2026
Same journal

Choroidal and Retinal Imaging Findings in Childhood-Onset Mevalonate Kinase Deficiency: An OCT-Based Case-Control Study.

Ocular immunology and inflammation·2026
See all related articles

Related Experiment Video

Updated: Jan 14, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.8K

Non-Neoplastic Disorders Mimicking Posterior Segment Inflammation.

Dimitrios Kalogeropoulos1, Kareem Moussa2, Ivan A Copado2

  • 1Stoke Mandeville Hospital, Buckinghamshire NHS Trust, Aylesbury, UK.

Ocular Immunology and Inflammation
|October 17, 2025
PubMed
Summary
This summary is machine-generated.

Ocular masquerade syndromes mimic intraocular inflammation but stem from non-inflammatory causes. Distinguishing these conditions from uveitis is crucial to prevent misdiagnosis and ensure appropriate treatment, preserving vision.

Keywords:
Differential diagnosisinherited retinal degenerationmasquerade syndromesposterior segment inflammationretinal imagingretinitis pigmentosauveitis

More Related Videos

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.1K
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

2.3K

Related Experiment Videos

Last Updated: Jan 14, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.8K
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.1K
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

2.3K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Pathology

Background:

  • Masquerade syndromes present as intraocular inflammation but have non-inflammatory origins.
  • Accurate differentiation from uveitis is vital to avoid incorrect treatment and vision loss.

Purpose of the Study:

  • To review non-neoplastic posterior segment masquerade syndromes.
  • To highlight their epidemiology, clinical features, imaging findings, and diagnostic challenges.

Main Methods:

  • Systematic review of literature on ocular masquerade syndromes.
  • Analysis of clinical presentation, multimodal imaging (OCT, FAF, FA, ICGA, ultrasonography), and diagnostic strategies.
  • Integration of history, examination, and laboratory testing.

Main Results:

  • Discussed conditions include inherited retinal degenerations, chronic endophthalmitis, retinal detachment, foreign bodies, uveal effusion, central serous chorioretinopathy, amyloidosis, Coats disease, persistent fetal vasculature, and X-linked retinoschisis.
  • Detailed distinguishing features from uveitis for each entity.
  • Proposed a diagnostic algorithm for early recognition.

Conclusions:

  • Early identification of masquerade syndromes is essential for appropriate management.
  • Avoiding unnecessary immunosuppression and optimizing visual outcomes are key goals.
  • A systematic diagnostic approach aids in differentiating these mimics from true uveitis.