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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

743
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
743
Depression: Overview01:18

Depression: Overview

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
777

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Related Experiment Video

Updated: Jan 14, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Maternal Attention Deficit Hyperactivity Disorder and Perinatal Depression: A Systematic Review.

Natalie Pierotti1, Kaushadh Jayakody1,2,3

  • 1Bendigo Health, Bendigo, VIC, Australia.

Journal of Attention Disorders
|October 18, 2025
PubMed
Summary
This summary is machine-generated.

Women with Attention Deficit Hyperactivity Disorder (ADHD) face a significantly higher risk of perinatal depression. This systematic review highlights the association between ADHD symptoms and increased vulnerability to depression during the perinatal period.

Keywords:
ADHDantenataldepressionperinatalpostnatal

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Area of Science:

  • Perinatal Mental Health
  • Neurodevelopmental Disorders
  • Psychiatry

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a persistent condition often comorbid with other mental health issues.
  • Limited research exists on ADHD in the perinatal period, despite increasing diagnoses in women of reproductive age.

Purpose of the Study:

  • To critically appraise existing literature on the association between maternal ADHD and perinatal depression.
  • To examine the prevalence and risk factors of perinatal depression in women with ADHD.

Main Methods:

  • A systematic review was conducted using EMBASE, PsycINFO, MEDLINE, and Google Scholar.
  • Literature was evaluated using PRISMA guidelines and quality assessed with the Joanna Briggs Institute framework.
  • A narrative synthesis of ten included studies was performed.

Main Results:

  • A prevalence of 16.76% to 57.6% for perinatal depression was found in women with ADHD.
  • Women with ADHD showed an increased risk of perinatal depression (OR 1.8-2.63).
  • A positive association was observed between ADHD symptoms and depressive symptoms in the perinatal period.

Conclusions:

  • Women with ADHD exhibit greater vulnerability to perinatal depression.
  • A clear association exists between ADHD symptoms and depressive symptoms during the perinatal period.
  • Further high-quality research is needed to validate these findings.