A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications

This review highlights the design and applications of various types of neutral organic superbases, a relatively new and widely adopted class of Brønsted bases. These superbases offer complementary properties to conventional inorganic bases and have found increasing commercial application in modern synthetic methodologies. The recent advances in the computational design, synthesis, and catalytic behavior of organic superbases have been summarized. This article would embolden the development of novel, highly effective, and selective catalysts that enable efficient chemical transformations under metal-free conditions.