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Published on: August 4, 2018
Foveal Avascular Zone Area in Patients with Systemic Lupus Erythematosus Using Optical Coherence Tomography
Ploysai Rujkorakarn1, Kanyanat Pholprathom2, Parinya Srihatrai2
1Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.
Purpose:
To evaluate the area of the superficial foveal avascular zone (SFAZ) and deep foveal avascular zone (DFAZ) in patients with systemic lupus erythematosus (SLE) using optical coherence tomography angiography (OCT-A) and to associate the SFAZ and DFAZ areas with medication.
Design:
A cross-sectional observational study.
Patients And Methods:
This study included 36 eyes of 36 SLE patients and 33 eyes of 33 healthy controls. SFAZ, DFAZ, and central retinal thickness (CRT) were measured using Spectralis OCT-A. Data on medical history and medications were collected to determine associations with SFAZ and DFAZ areas.
Results:
SFAZ and DFAZ areas showed no significant association with hydroxychloroquine/chloroquine duration or immunosuppressive therapy (p>0.05).
Conclusion:
The SFAZ and DFAZ areas in patients with SLE were not significantly larger than those in healthy controls. However, the CRT was significantly thinner.
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