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Updated: Jan 14, 2026

Dissection and 2-Photon Imaging of Peripheral Lymph Nodes in Mice
Published on: August 23, 2007
Resolution in Two-Photon Imaging: A Local Manifestation of Entanglement
T Gregory1, E Toninelli1,2, P-A Moreau1,3,4
1School of Physics and Astronomy, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Abstract:
The resolution of a classical imaging system is limited by diffraction. This limit can be overcome, for example, by implementing various forms of localization microscopy in which the center of a fluorescence distribution is estimated to an accuracy scaling with the square root of the number of detected photons, . In quantum imaging the object can be illuminated using correlated photon-pairs, leading early work to suggest that a improvement could be obtained as a result of averaging the position of N = 2 events. However, similar to quantum lithography, which relies upon quantum illumination using entangled photon-pairs and two-photon absorption, the minimum resolvable feature size is reduced by a factor of 2, not just . Quantum imaging schemes can also lead to a factor of 2 improvement. By using a similar source of correlated photon-pairs to illuminate an object, a single-photon sensitive camera to detect the photon-pairs, and an image processing algorithm to record and sum the bisector positions of the transmitted photon-pairs, we realize a similar factor of ×2 improvement in image resolution, surpassing that of most earlier quantum imaging work.

