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Myocardial Necrosis in a Child After COVID-19: A Case Report

Faeze Keihanian1, Hassan Mottaghi Moghaddam Shahri2, Amin Saeidinia2

  • 1Cardiology Department, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.

Clinical Case Reports
|October 20, 2025
PubMed

Insights

COVID-19 can cause rare heart attacks in children. This case highlights the need to consider coronary artery thrombosis in pediatric patients with COVID-19 and cardiac symptoms.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Cardiovascular Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) has caused significant global health issues.
  • While rare, pediatric myocardial infarction (MI) can occur.
  • COVID-19 may increase inflammation and blood clotting, potentially leading to coronary thrombosis and MI in children.

Purpose of the Study:

  • To report a rare case of ST-elevation myocardial infarction (STEMI) in a pediatric patient.
  • To investigate the link between COVID-19 and coronary artery thrombosis in children.
  • To raise awareness about potential cardiac complications of COVID-19 in pediatric populations.

Main Methods:

  • Case report of an unvaccinated 4-year-old boy.
  • Clinical presentation and diagnostic workup for STEMI.
  • Assessment of COVID-19 related hyperinflammation and hypercoagulability.

Main Results:

  • The patient developed STEMI.
  • Coronary artery thrombosis secondary to COVID-19 was identified as the cause.
  • This highlights a rare but serious complication of COVID-19 in children.

Conclusions:

  • COVID-19 can precipitate coronary artery thrombosis and MI in pediatric patients.
  • Acute coronary events should be considered in children with COVID-19 presenting with cardiac symptoms.
  • Further research is needed to understand the full spectrum of COVID-19 cardiac complications in children.

Keywords:
childrenmultisystem inflammatory syndrome in childrenmyocardial infarctionmyocardial necrosis

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