Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Polymer Classification: Stereospecificity

Polymer Classification: Stereospecificity

Polymerization generates chiral centers along the entire backbone of a polymer chain. Accordingly, the stereochemistry of the substituent group has a significant effect on polymer properties. Polymers formed from monosubstituted alkene monomers feature chiral carbons at every alternate position in the polymer backbone. Relative to the predominant orientation of substituents at the adjacent chiral carbons, the polymer can exist in three different configurations: isotactic, syndiotactic, and...

Classification of Titrimetric Analysis Based on Reaction Types

Classification of Titrimetric Analysis Based on Reaction Types

Titrimetric analysis in solution chemistry involves measuring the volume of solutions and is often called volumetric analysis. The standard solution of known concentration in the burette is called the titrant, whereas the solution of unknown concentration in the flask is called the analyte, or titrand. Titrimetric analyses can be classified into four types based on the reactions between the titrant and analyte.
Titrations between an acid and a base lead to neutralization reactions that form...

Ion Exchange

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or basic...

Chromatographic Methods: Classification

Chromatographic Methods: Classification

Chromatographic techniques are classified in three ways: the classification is based on the physical state of the stationary and mobile phases, how the mobile phase and the stationary phase contact each other, or through the chemical or physical processes that isolate the components of the sample. Typically, the mobile phase is either a liquid or gas, while the stationary phase is either a solid or a liquid layer applied to a solid surface.
Chromatographic techniques are typically named by...

Classification and Mechanical Properties of Synthetic Polymers

Classification and Mechanical Properties of Synthetic Polymers

Synthetic polymers are classified as elastomers, fibers, or plastics based on their crystallinity. Crystallinity, the degree of long-range order in the solid state, influences the mechanical properties (stretching or contracting) of elastomers. Elastomers are flexible polymers that can expand or contract easily upon the application of an external force. They have numerous crosslinks that pull them back into their original shape when stress is removed. Silicones, for instance, are highly elastic...

Passive Diffusion: Overview and Kinetics

Passive Diffusion: Overview and Kinetics

Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting their diffusion into...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Plug flow down to the nanoscale can induce partial solidification of confined fluids.

Soft matter·2026

Same author

Confinement-induced collective motion in suspensions of run-and-tumble particles.

The Journal of chemical physics·2026

Same author

The problem of the mechanical surface tension of active Brownian particle interfaces.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Structural and dynamic anomalous properties of TIP4P/2005 water at extreme pressures.

The Journal of chemical physics·2026

Same author

Effective interactions in active Brownian particles.

Soft matter·2026

Same author

Collective filament wrapping and nested spiral formation in active polydisperse systems.

Soft matter·2026

Same journal

Dual-mode pH-programmable enzymatic hydrogel system for on-demand glucose generation.

Soft matter·2026

Same journal

Loading iron(III)porphyrin as the gas/anion binding site into methylated β-cyclodextrin-incorporated polymer hydrogels.

Soft matter·2026

Same journal

Disorder-induced persistent random motion and trapping of microswimmers.

Soft matter·2026

Same journal

Metal-ion induced coacervation of a short peptide under acidic conditions.

Soft matter·2026

Same journal

Charles Murray van Wyk, a discreet pioneer of fibre network mechanics.

Soft matter·2026

Same journal

Volume and surface methods for microparticle traction force microscopy: a computational and experimental comparison.

Soft matter·2026

See all related articles

Search research articles

Home
Sorting Of Binary Active-passive Mixtures In Designed Microchannels.

Home
Sorting Of Binary Active-passive Mixtures In Designed Microchannels.

Related Experiment Video

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Sorting of binary active-passive mixtures in designed microchannels.

Horacio Serna^1,2, C Miguel Barriuso G^1,2, Ignacio Pagonabarraga^3,4

¹Departamento de Estructura de la Materia, Física Térmica y Electrónica, Universidad Complutense de Madrid, 28040 Madrid, Spain. cvaleriani@ucm.es.

|October 20, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

This study enhances passive particle transport in active-passive mixtures using computational simulations. Optimizing active particle tumbling rates and microchannel geometry maximizes passive particle movement and mixture sorting efficiency.

More Related Videos

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

Related Experiment Videos

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

Area of Science:

Physics, Soft Matter
Biophysics
Chemical Engineering

Background:

Microscale mixtures of active and passive particles are common in biological systems.
Passive particle transport is influenced by active agents, impacting processes like cargo delivery.
Understanding active-passive interactions is key for microscale applications.

Purpose of the Study:

To investigate the transport properties of passive particles in active-passive mixtures within confined microchannels.
To explore how active particle dynamics and microchannel geometry affect passive particle movement and mixture separation.
To identify conditions for maximum enhancement of passive particle transport and sorting efficiency.

Main Methods:

Computational simulations of active-passive particle mixtures in microchannels with funnel-like obstacles.

Modeling active particles with Langevin translational and run-and-tumble rotational dynamics.

Analyzing the effects of active particle tumbling rates and microchannel geometry on passive particle transport.

Main Results:

Adjusting active particle tumbling rates and microchannel geometry significantly enhances passive particle transport (diffusion coefficient, advective velocity).
Maximum enhancement correlates with high mixture sorting efficiency and rapid response times.
Active drift, not just thermal or active diffusion, drives enhanced mixture separation.

Conclusions:

Active-passive mixtures offer tunable transport properties for passive particles.
Microchannel design and active agent dynamics are critical for optimizing microscale separation and transport.
This work provides a foundation for designing systems for efficient microscale cargo delivery and bioremediation.