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Direct cost savings associated with reduction in plasma metagenomic sequencing
Caitlin Naureckas Li1,2, Neil Jordan1, Shannon Haymond1,3
1https://ror.org/000e0be47Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Infection Control and Hospital Epidemiology
|October 21, 2025
Abstract
None:
Following recognition that our hospital had higher use of plasma metagenomic next-generation sequencing than our peers, we implemented a process for approval by infectious diseases before test collection. This intervention is calculated to result in a direct cost savings of $79,505-$84,057/year, driven mainly by reduced laboratory costs.

