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Updated: Jan 14, 2026

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
Published on: August 7, 2013
The enteric nervous system
David R Linden1, Keith A Sharkey2
1Enteric Neuroscience Program, Mayo Clinic, Rochester, MN 55905, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Abstract:
The enteric nervous system (ENS) is a unique component of the autonomic nervous system found within the wall of the gastrointestinal (GI) tract. What distinguishes the ENS is its size, containing as many neurons as the spinal cord, and its ability to function in the absence of connections to the central nervous system.
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