Related Experiment Video
Updated: Jan 14, 2026

Live Imaging of Nicotine Induced Calcium Signaling and Neurotransmitter Release Along Ventral Hippocampal Axons
Published on: June 24, 2015
An Observational Study of Nicotine Replacement Therapy Availability Through Pharmacist Prescribing in the California
Deanna M Halliday1, Sara Schneider2, Tanner Wakefield1,3
1Center for Tobacco Control Research and Education, UCSF Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
Background:
California's Central Valley has high rates of tobacco product use and low rates of access to healthcare providers, making it difficult for residents to acquire effective tobacco cessation treatment. To address this disparity, California pharmacists can act as healthcare providers, with the ability to provide counseling and independently prescribe nicotine replacement therapy (NRT) medications through a process known as "furnishing".
Methods:
All corporate and independent pharmacies in the Central Valley who serve the general community were contacted (n = 586) to ask whether pharmacists furnished NRT. The authors visited pharmacy locations (n = 23) that indicated they furnished NRT to request participation in a survey and interview. The authors analyzed if pharmacies furnished NRT, the characteristics of those that furnished, the creation of implementation of protocols, barriers, and facilitators, and how services were fostered.
Results:
In interviews, pharmacists expressed generally positive attitudes toward furnishing, but were concerned about barriers, including concerns about feasibility and affordability, lack of administrative support, and perceived limited demand.
Conclusions:
Despite the region's high tobacco usage rates, few pharmacies (n = 5; 0.88%) furnished NRT. To increase furnishing rates, corporate policy changes, recognition of pharmacists as providers by insurance companies, and support from the California Board of Pharmacy are likely needed. Increasing advertising, building rapport, and knowing patients' tobacco history may increase NRT utilization.
Related Concept Videos
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
Methods for Studying Drug Absorption: In situ
The Doluisio method involves perfusing a prepared segment of a rat's small intestine with a solution of radiolabeled drug and a non-absorbable marker. This helps to differentiate between absorbed and non-absorbed drug concentrations. The intestinal segment is connected at both ends using tubing and syringes,...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Analysis of Population Pharmacokinetic Data

