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Related Concept Videos

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Updated: Jan 14, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
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Experiencing Sepsis: A Meta-Ethnography.

Marie W Sim Johnston1, Amy J Lorimer1, Kimberley J Haines2,3

  • 1St John of God Midland Public and Private Hospitals, Perth, WA, Australia.

Critical Care Medicine
|October 22, 2025
PubMed
Summary
This summary is machine-generated.

Sepsis survivors face dependency, psychological challenges, and post-discharge issues. Caregivers experience strain and uncertainty, highlighting the need for improved survivorship care and support.

Keywords:
Sepsiscaregiversmeta-ethnographypatientsqualitative researchquality of lifesurvivors

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Area of Science:

  • Critical care medicine
  • Qualitative health research
  • Patient and caregiver experience

Background:

  • Sepsis survivors often experience profound physical, psychological, and social challenges post-discharge.
  • Caregivers of sepsis survivors also face significant emotional, financial, and logistical burdens.
  • Understanding these lived experiences is crucial for developing effective recovery support.

Purpose of the Study:

  • To synthesize the adverse and transformative experiences of adult sepsis survivors and their caregivers.
  • To generate experience-based insights to inform recovery support and future care strategies.
  • To identify key themes in sepsis survivorship from the perspective of those affected.

Main Methods:

  • A meta-ethnographic approach guided the synthesis of qualitative and mixed-methods studies.
  • Searched five databases (MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) from 2000-2025.
  • Nine eligible studies reporting on adult sepsis survivor and caregiver experiences were included.

Main Results:

  • Survivor themes included increased dependency, 'ICU fog,' psychological adjustment, relationship dynamics (gratitude/guilt), and post-discharge challenges.
  • Caregiver themes comprised adapting to caregiving, future uncertainty, and communication difficulties.
  • Dependency significantly impacted survivors' autonomy and identity, while caregivers faced substantial strain.

Conclusions:

  • Consistent themes emerge across individual sepsis survivorship journeys.
  • Survivor and caregiver experiences highlight critical areas for intervention and research.
  • Enhanced survivorship care requires prioritizing psychological support, communication, and post-discharge services.