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Sample Preparation for Analysis: Overview

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Related Experiment Video

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Transcript and Metabolite Profiling for the Evaluation of Tobacco Tree and Poplar as Feedstock for the Bio-based Industry

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A Workflow for Selecting, Profiling, and Optimizing Plant Extracts for Cosmetic Applications.

Maria Viéytez¹, Aline Robert-Hazotte², Amélie Thomas³

¹Institut De Chimie de Nice, Université Côte d'Azur, Nice, France.

Chemistry & Biodiversity

|October 22, 2025

Summary

This summary is machine-generated.

This study presents a method for finding new cosmetic ingredients from French plants. Controlled cultivation of borage (Borago officinalis L.) enhanced its antioxidant properties, showing potential for optimizing natural ingredients.

Keywords:

antioxidant activity cosmetic bioassay natural cosmetic ingredient phytocosmetics rotational cultivation

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Area of Science:

Cosmetic Science
Phytochemistry
Agricultural Science

Background:

Growing demand for innovative natural cosmetic ingredients.
Need for structured approaches to identify and validate bioactive plant species.
Exploration of French flora for cosmetic applications.

Purpose of the Study:

To develop a structured workflow for identifying novel, bioactive plant species in France for cosmetic applications.
To assess the impact of controlled cultivation methods on the bioactivity of selected plant species.
To highlight promising plant-derived natural active ingredients for the cosmetics industry.

Main Methods:

Screening of 1614 plant species for regulatory and innovation potential.
Phytochemical profiling using High-Performance Liquid Chromatography (HPLC)-Diode Array Detector (DAD)/Evaporative Light Scattering Detector (ELSD).
In vitro antioxidant and enzymatic assays, coupled with a dual scoring system for bioactivity and novelty.
Case study involving indoor cultivation of Borago officinalis L. using rotational geoponics.

Main Results:

Four promising plant species were identified for cosmetic development based on bioactivity and novelty.
Borago officinalis L. exhibited enhanced antioxidant properties when cultivated indoors under controlled, low-temperature conditions.
A replicable workflow for sourcing and optimizing plant-based active ingredients was established.

Conclusions:

A systematic approach can effectively identify novel natural ingredients for cosmetics.
Tailored cultivation techniques, such as controlled indoor geoponics, can significantly enhance the performance of plant-derived compounds.
This research provides a framework for unlocking the potential of underexploited plant species for cosmetic innovation.