The association between electrical risk score and non-dipper hypertensive pattern with newly diagnosed hypertensive...

The electrical risk score (ERS) is composed of six simple electrocardiography (ECG) parameters: heart rate, presence of left ventricular hypertrophy, QRS transition zone, corrected QT interval, T-peak-to-T-end interval and frontal QRS-T angle. ERS has been shown to improve risk assessment for various diseases.

This study aimed to investigate the relationship between ERS and circadian blood pressure variability.

This study recruited 144 hypertensive individuals who underwent 24 h ambulatory blood pressure monitoring (ABPM). Based on the findings of 24 h ABPM, the study population was categorized into the following two groups: patients with dipper hypertension (HT) and those with non-dipper HT. ERS was measured using 12-lead ECG.

The ERS in individuals with non-dipper HT was substantially greater than in patients with dipper HT (2.75±1.07 vs. 2.31±1.03 respectively, p = 0.018). ERS (OR:1.507, 95 % CI:1.060- 2.142; p = 0.022) was independently associated with non-dipper HT according to multivariate analysis. An optimal ERS cut-off value of >2 predicted a non-dipper hypertensive pattern with 59.1 % sensitivity and 56.9 % specificity ([AUC]: 0.604 [95 % CI: 0.519-0.684, p = 0.0263]).

This study showed that increased ERS was associated with non-dipper pattern in newly diagnosed patients with HT.