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Related Experiment Video

Updated: May 8, 2026

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments
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Automated smartphone based cell analysis platform.

Meryem Beyza Avci1,2,3, Fatma Kurul1, Mehmet Turkan2

  • 1Izmir Biomedicine and Genome Center, Izmir, Turkey.

Npj Imaging
|October 22, 2025
PubMed
Summary
This summary is machine-generated.

Quantella is a new smartphone-based cell analysis platform. This accessible technology provides accurate cell viability, density, and confluency measurements, overcoming limitations of traditional methods.

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Area of Science:

  • Biomedical Engineering
  • Cell Biology
  • Medical Diagnostics

Background:

  • Cell analysis is crucial for biomedical research, but conventional systems are costly and complex.
  • Existing technologies often lack adaptability and accessibility for diverse research settings.

Purpose of the Study:

  • To introduce Quantella, a novel smartphone-based platform for comprehensive cell analysis.
  • To address the limitations of current cell analysis technologies, focusing on cost, complexity, and adaptability.

Main Methods:

  • Quantella integrates low-cost optics, a rinsable flow cell, Bluetooth control, and a mobile app.
  • An adaptive image-processing pipeline with multi-exposure fusion, thresholding, and morphological filtering enables morphology-independent segmentation.
  • The system was validated across diverse cell types against flow cytometry.

Main Results:

  • Quantella achieved deviations under 5% compared to flow cytometry.
  • The platform can analyze over 10,000 cells per test, delivering high-throughput and reproducible results.
  • The image-processing pipeline accurately segments cells without deep learning or user-defined parameters.

Conclusions:

  • Quantella offers an accessible and scalable solution for cell analysis, including viability, density, and confluency.
  • Its design makes it suitable for biomedical research, diagnostics, and education, especially in resource-limited environments.
  • This technology democratizes advanced cell analysis capabilities.