[Effect of a poly I-poly C complex with poly-L-lysine on experimental tick-borne encephalitis]

The influence of the poly(I)-poly(C) complex with poly-l-lysine on the development and course of experimental tick-borne encephalitis was studied in Macaca rhesus monkeys. Prophylactic administration of the substance under study, although not preventing the disease, modified its course and facilitated recovery of the animals. Poly(I)-poly(C) and its complex with poly-l-lysine were shown to have no effect on production of infectious virus or its antigen demonstrable by the immunofluorescence procedure in HEp-2 cells chronically infected with tick-borne encephalitis virus.