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Break free from cognitive impairment: The magic of exercise-induced molecules
Wenbo Liu1, Hui Zhang1, Qiuting Zeng1
1Department of Anesthesiology & Key Laboratory of Clinical Science and Research, Department of Anesthesiology, Zhongda, Hospital, Medical School, Southeast University, China.
None:
•Exercise-induced molecules regulate cognition via trophic, immune, and metabolic pathways.•Muscle-brain crosstalk contributes to cognitive resilience in aging and neurodegeneration.•CTSB, lactate and others show dual roles-protective yet potentially pathological-depending on context.•Translational perspective: target exercise-mimetic molecules as non-pharmacological options for cognitive disorders.
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