Related Experiment Video
Updated: Jan 14, 2026

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
Published on: May 12, 2023
[Bispecific antibodies: indications and perspectives in onco-hematology]
Léa Fornero1, Guillaume Cartron1
1Département d'hématologie clinique, CHRU de Montpellier, France.
Bispecific Antibodies:
INDICATIONS AND PERSPECTIVES IN ONCO-HEMATOLOGY. Bispecific antibodies, currently under active development, are a new and effective therapeutic tool in malignant hematological diseases. Those used in clinical practice aim to restore the recognition of tumor cells by immune effector cells, leading to their direct and targeted cytotoxicity through the formation of an immune synapse. The main current indications are acute lymphoblastic leukemias, diffuse large B-cell lymphomas, and multiple myeloma, refractory or in relapsed after conventional treatment. Due to their efficacy and tolerance profile, research on bispecific antibodies is highly active and aims to expand their indications.
More Related Videos
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against...
Tumor Immunotherapy
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Regulation of Hematopoietic Stem Cells

