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Updated: Jan 14, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Opioids and Respiratory Related Consequences
Jeremy E Orr1, Deanna Hill1, Robert L Owens1
1Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Abstract:
Opioids are widely used in acute and chronic pain management, but have significant respiratory effects that pose risks, especially in hospital settings. Opioid-induced respiratory depression occurs with opioids suppress the body's respiratory rate and response to CO2, leading to life-threatening gas exchange impairment. Chronic use of opioids causes central sleep apnea with an irregular breathing pattern, and contributes to complexity in managing obstructive sleep apnea. Mitigating respiratory risks of opioids involves limiting doses, careful monitoring, and sometimes the use of respiratory support like non-invasive ventilation.
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