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Intracranial Pharmacotherapy and Pain Assays in Rodents
Published on: April 9, 2019
Pharmacology of Pain Management
Brian Cornelius1, Bailey Freeman1, Angela Mordecai1
1Graduate Program in Nurse Anesthesia, Texas Wesleyan University, 1201 Wesleyan Street, Fort Worth, TX 76105, USA.
Abstract:
This article reviews various pharmacologic approaches for pain management, highlighting traditional and emerging therapies. Opioids, while effective, pose significant risks such as tolerance and addiction, prompting the adoption of multimodal analgesia. Topical anesthetics, acetaminophen, nonsteroidal anti-inflammatory drugs, and steroids offer alternative or adjunctive pain control. Antiepileptics and antidepressants are particularly useful for neuropathic pain, while muscle relaxants address musculoskeletal conditions. Understanding the pharmacologic properties, therapeutic applications, and safety profiles of these agents is essential for optimizing individualized pain management. Ongoing research focuses on enhancing efficacy, reducing adverse effects, and identifying new agents that can address the complexities of chronic pain.
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