The relationship between oxidative balance score and metabolic syndrome

The Oxidative Balance Score (OBS) is a comprehensive biomarker that assesses an individual's oxidative/antioxidative status, encompassing both dietary and lifestyle aspects. Excessive oxidative stress has been associated with the occurrence of metabolic syndrome (MetS), making the exploration of the relationship between OBS and MetS crucial for understanding metabolic health. This study utilized data from the National Health and Nutrition Examination Survey for the years 2007 to 2014. Through questionnaire surveys and data analysis, the OBS was calculated, and an assessment of MetS and its constituent factors was conducted. Logistic regression analysis was employed to clarify the relationship between OBS and the risk of MetS. Pearson correlation analysis was used to describe the relationship between OBS and the abnormal quantity of MetS components. Subgroup analysis and sensitivity analysis were also conducted to elucidate the stability and generalizability of the results. A total of 19,289 participants were included in this study, with an average age of 46.93 ± 16.55 years. An increase in OBS, whether attributed to dietary or lifestyle OBS, is associated with a reduced risk of developing MetS (odds ratio = 0.87, 95% confidence interval: 0.82-0.93). Specifically, OBS is negatively correlated with the abnormal quantity of MetS components. This association remains stable across different subgroups and sensitivity analyses. This study has unveiled the relationship between OBS and MetS in the American population. An elevated OBS is significantly associated with a reduced risk of MetS. Improving dietary and lifestyle linked to OBS may contribute to the prevention and management of MetS.