Related Experiment Video

Updated: Jan 14, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
07:26

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

7.7K

Stroke, infections, and New Mechanisms: a Narrative Review

Jacques Reis1,2, Şerefnur Öztürk3, Alain Buguet4

  • 1Department of Neurology, University Hospital Hautepierre, Strasbourg, 67200, France. jacques.reis@wanadoo.fr.

Current Neurology and Neuroscience Reports
|October 25, 2025
PubMed
Abstract

Insights

Infections are an underrecognized cause of stroke, impacting both ischemic and hemorrhagic types. Recognizing this link is crucial for developing better prevention and treatment strategies, especially with changing global conditions.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • The link between infections and stroke has been known for over 60 years but remains underrecognized.
  • Recent global events, like the COVID-19 pandemic, have increased awareness of infectious agents as potential health risks.

Purpose of the Study:

  • To assess preceding infections as triggers or causal factors for ischemic and hemorrhagic stroke.
  • To highlight the underappreciated role of infections, including tropical infections, in stroke etiology.
  • To emphasize the need for greater recognition of infection-related stroke risk.

Main Methods:

  • Review of existing literature on infections as stroke risk factors.
  • Analysis of the impact of various infectious agents (bacteria, viruses, fungi, parasitosis).
  • Consideration of confounding factors like meteorological conditions and air pollution.

Main Results:

  • Infections are a significant, yet often overlooked, risk factor for stroke.
  • The risk posed by infectious agents is primarily recognized in pediatric and young adult populations.
  • Meteorological factors may obscure the direct link between infections and stroke incidence.

Conclusions:

  • Enhanced recognition of infection-related stroke risk is essential for public health.
  • Factors like global warming may increase stroke incidence due to infections.
  • Biomarkers and improved preventive/therapeutic strategies are needed to address this growing concern.
Keywords:
COVID-19Climate changeDental infectionsExtracellular vesiclesStroke prevention.Tropical infections

More Related Videos

Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots06:12

Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots

Published on: July 21, 2023

1.0K
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.4K

Related Concept Videos

Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
563
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
382
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
278
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
413
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
317
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
210