Related Experiment Video
Updated: Jan 14, 2026

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
Published on: July 12, 2024
Air pollution and risk of rheumatoid arthritis - A Danish register-based cohort study
Regitze Sølling Wils1, Helena Breth Nielsen2, Esben Meulengracht Flachs1
1Department of Occupational and Environmental Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
Abstract:
This study examined the association between ambient air pollution and risk of rheumatoid arthritis (RA). Individuals born 1960-1999 from the nationwide Danish Occupational Cohort with eXposure data were linked to modeled exposure at the home address(es) and RA hospital diagnoses (N = 2,092,596). Recent and 10-years cumulative exposure to particles ≤ 2.5 (PM2.5) and ≤ 10 µm (PM10), nitrogen oxide (NO2) and elemental carbon (EC) were subdivided into quartiles, and risk of incident RA (1997-2018) were calculated using Poisson regression analyses. Recent and cumulative exposure to PM2.5, NO2 and EC increased risk of RA, for all quartiles compared to the lowest quartile, but without a clear exposure-response relationship. Analyses stratified on sex generally showed similar trends, yet small differences were seen for PM2.5 and EC (differences between IRR for men and women in model 2: PM2.5 0.03-0.19, and EC 0.05-0.14). Higher risks were indicated for exposure to PM2.5 and PM10 for age below as compared to above 40 years. In conclusion, exposure to PM2.5, NO2 and EC increased risk of RA, with little influence from sex and some influence of age.
More Related Videos
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
08:47Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Asthma-I: Introduction
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
The JAK-STAT Signaling Pathway
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease I: Introduction