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Maternal Primary Sjögren's Syndrome Complicated by Irreversible Fetal Third-Degree Congenital Heart Block: A Case
Priety Shah1, Pramit Jaiswal2, Pukar Adhikari3
1Department of Obstetrics and Gynecology Kathmandu Medical College and Teaching Hospital Kathmandu Nepal.
In pregnancies of anti-Ro/SSA- and anti-La/SSB-positive women with primary Sjögren's syndrome, third-degree fetal congenital heart block is usually irreversible despite corticosteroids. Preconception counseling, hydroxychloroquine prophylaxis, and serial fetal echocardiography from 16 weeks are essential to enable timely counseling, including discussion of termination in poor prognosis cases.
In pregnancies of anti-Ro/SSA- and anti-La/SSB-positive women with primary Sjögren's syndrome, third-degree fetal congenital heart block is usually irreversible despite corticosteroids. Preconception counseling, hydroxychloroquine prophylaxis, and serial fetal echocardiography from 16 weeks are essential to enable timely counseling, including discussion of termination in poor prognosis cases.
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