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Abnormal Proliferation02:23

Abnormal Proliferation

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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[Aberrant TTF1 expression in anaplastic large cell lymphoma].

V A Khorzhevskii1, S V Gappoev1, Y S Kanin2

  • 1Krasnoyarsk State Regional Bureau of Pathology, Krasnoyarsk, Russia.

Arkhiv Patologii
|October 27, 2025
PubMed
Summary

Thyroid transcription factor 1 (TTF1) aberrant expression was found in 10.6% of anaplastic large cell lymphoma cases. This finding is crucial for accurate lymphoma diagnosis, preventing misinterpretation as metastatic disease.

Area of Science:

  • Oncology
  • Pathology
  • Immunohistochemistry
Keywords:
TTF1aberrant expressionanaplastic large cell lymphoma

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