Stroke Occurring in 18 F-FDG PET/CT Session
Friedrich Weitzer1, Birgit Pernthaler2, Susanne Stanzel1
1Department of Radiology, Division of Nuclear Medicine, Medical University of Graz.
Clinical Nuclear Medicine
|October 27, 2025
Summary
18F-FDG PET/CT detected lung adenocarcinoma metastasis in a patient experiencing severe headaches. Subsequent cranial imaging revealed a critical intracerebral hematoma with significant brain shift.
Area of Science:
- Nuclear Medicine
- Neurology
- Oncology
Background:
- 18F-FDG PET/CT is a standard imaging modality for cancer staging and restaging.
- Intracerebral hemorrhage can present with diverse neurological symptoms.
Purpose of the Study:
- To report a case of incidental finding of intracerebral hematoma during PET/CT for lung cancer restaging.
- To highlight the utility of PET/CT in detecting acute intracranial events.
Main Methods:
- Whole-body 18F-FDG PET/CT was performed for lung adenocarcinoma restaging.
- A dedicated cranial PET/CT scan was conducted due to patient symptoms.
- Contrast-enhanced cranial CT was performed for further evaluation.
Main Results:
- Initial PET/CT showed a hypermetabolic lesion in the right lung, suspicious for metastasis.
- Cranial PET/CT revealed an intracerebral hematoma and glucose hypometabolism in the left occipital lobe.
- Follow-up CT demonstrated progressive hematoma, midline shift, and tentorial herniation.
Conclusions:
- 18F-FDG PET/CT can incidentally detect acute intracranial pathology.
- Prompt recognition of intracerebral hematoma is crucial for timely intervention.
- This case underscores the importance of considering neurological emergencies during oncologic imaging.
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