[Research progress on central nervous system changes in chronic ankle instability and its implications for treatment]

The objective of this review was to summarize the latest research progress in the past five years on changes in central nervous system (CNS) function in patients with chronic lateral ankle instability (CLAI). Previous studies suggested that alterations in CNS function might be a potential factor contributing to CAI-related impairments. In recent years, with advancements in research techniques, it has been discovered that ankle disfunction in CAI patients may be associated with abnormalities in CNS function, such as changes in neuromuscular control and sensory-pain mechanisms. Based on the current understanding of CNS functional changes in CAI patients, various treatment approaches targeting the CNS functions have emerged. These interventions aim to improve neurological function in such patients, providing more precise and effective conservative treatment options for individuals with CAI.