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Updated: Jan 13, 2026

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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1-Nitro-2-Phenylethane as a Multitarget Candidate for Cognitive and Psychiatric Disorders: Insights from In Silico

Emily Christie Maia Fonseca1, Lucas Villar Pedrosa da Silva Pantoja1,2, Daniele Luz de Campos3

  • 1Programa de Pós-Graduação em Farmacologia e Bioquímica, Universidade Federal do Pará, Belém 66075-900, PA, Brazil.

Pharmaceuticals (Basel, Switzerland)
|October 29, 2025
PubMed
Summary

1-nitro-2-phenylethane (1N2PE) shows promise for neurological and psychiatric disorders. This natural compound improved memory, reduced anxiety, and demonstrated antidepressant-like effects in preclinical studies.

Keywords:
Aniba canelillabioactive compoundcognitionessential oilnatural productspsychiatric disorder

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