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Updated: Jan 13, 2026

Preparation of Naringenin Solution for In Vivo Application
Published on: August 10, 2021
Potential and Mechanism of Nobiletin in Diabetes Mellitus and Associated Complications
Chuyun Zhao1, Wenjie Lai1, Yu Li2
1School of Pharmacy, Faculty of Medicine & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Abstract:
The incidence and mortality of diabetes have increased dramatically in recent decades. New strategies to treat diabetes and its complications with minimal side effects are urgently needed. New monomeric molecules extracted from herbs are an alternative medicine that is being explored as candidate drugs for the treatment of diabetes and its complications. Nobiletin, a citrus flavonoid, has recently received increasing attention in scientific research due to its properties in combating diabetes and its complications, while existing research is scattered and unsystematic. This article summarizes recent studies and reviews the potential therapeutic role of nobiletin in preventing and alleviating diabetes and its complications, aiming to provide promising strategies for the clinical management of diabetes and its complications.
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