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Updated: Jan 13, 2026

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
Persistent Liver Manifestations in Allopurinol-Induced Sweet's Syndrome: An Uncommon Case Report
Amalia Papanikolopoulou1, Sofia M Siasiakou1, Kosmas Pantazopoulos1
1Third Department of Internal Medicine, Sotiria General Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Drug-induced Sweet's syndrome (SS) can affect the liver, even without prior liver disease. This case highlights rare persistent hepatic abnormalities in SS, emphasizing the need for careful monitoring and management.
Area of Science:
- Dermatology
- Hepatology
- Internal Medicine
Background:
- Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition with potential systemic involvement.
- Liver involvement in SS is attributed to neutrophilic infiltration, reflecting the disorder's systemic inflammatory nature.
- Prompt diagnosis, exclusion of other causes, and corticosteroid treatment are crucial for managing SS.
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