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Related Experiment Video

Updated: Jan 13, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
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Epidemiology, Risk Factors, and Predictive Modelling of Post-Traumatic Sepsis: A Retrospective Cohort Study.

Xue Fu1, Zhen-Yi Wang2, Yan-Jun Qin1

  • 1Department of Emergency Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, 050011, People's Republic of China.

Risk Management and Healthcare Policy
|October 29, 2025
PubMed
Summary
This summary is machine-generated.

Post-traumatic sepsis is often caused by traffic accidents. Key risk factors include injury severity and hospitalization length, with age and organ failure predicting mortality.

Keywords:
ISSROC curveSOFA scoreepidemiological characteristicspost-traumatic sepsispredictive modellingreceiver operating characteristic curverisk factor

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Area of Science:

  • Trauma and Emergency Medicine
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Post-traumatic sepsis is a significant complication following traumatic injuries.
  • Understanding its epidemiological characteristics and risk factors is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the distribution spectrum and epidemiological characteristics of post-traumatic sepsis.
  • To identify associated risk factors for sepsis development and mortality in trauma patients.

Main Methods:

  • Retrospective analysis of 722 trauma patients admitted between January 2021 and November 2023.
  • Categorization into sepsis and non-sepsis groups, with sepsis survivors and non-survivors further analyzed.
  • Multivariate logistic regression used to identify independent risk factors for sepsis and mortality.

Main Results:

  • 189 out of 722 trauma patients developed sepsis, with traffic accidents being the primary cause.
  • Pulmonary infection was the most common infection site in both survivors and non-survivors.
  • Predictive models for sepsis and mortality demonstrated high accuracy (AUROC 0.998 and 0.969, respectively).

Conclusions:

  • Traffic accidents are a major cause of post-traumatic sepsis.
  • Injury severity, CRP levels, and hospitalization duration are key risk factors.
  • Age, organ failure score, and vasoactive drug use predict 28-day mortality.