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Published on: September 2, 2022
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Soy Protein Isolate/Tremella Fuciformis Polysaccharide Complex-Stabilized High Internal Phase Pickering Emulsions:
Yubo Cao1, Donggui Wang1, Quanshu Wang1
1College of Food Science and Engineering, Nanjing University of Finance and economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, China.
Langmuir : the ACS Journal of Surfaces and Colloids
|October 29, 2025
Summary
This study developed novel soy protein isolate and Tremella fuciformis polysaccharide complexes for advanced bioactive delivery systems. These complexes create stable emulsions with enhanced nutraceutical protection and bioaccessibility, ideal for 3D-printed functional foods.
Area of Science:
- Food Science and Technology
- Materials Science
- Biotechnology
Background:
- Advanced bioactive delivery systems are crucial for nutraceutical stability and controlled release.
- High internal phase Pickering emulsions (HIPPEs) offer potential but require effective stabilization.
- Soy protein isolate (SPI) and Tremella fuciformis polysaccharide (TFP) are promising natural stabilizers.
Purpose of the Study:
- To fabricate and characterize HIPPEs stabilized by SPI/TFP complexes.
- To evaluate the physicochemical properties and stability of optimized SPI/TFP HIPPEs.
- To assess the efficacy of SPI/TFP HIPPEs for andrographolide (Andr) delivery and 3D printing applications.
Main Methods:
- Fabrication of SPI/TFP complexes and HIPPEs.
- Characterization of complex interactions, emulsion properties (droplet size, zeta potential, rheology), and microstructure.
- In vitro assessment of Andr protection against stress and in vitro digestion studies.
- Evaluation of 3D printability and mechanical properties of Andr-loaded HIPPEs.
Main Results:
- SPI/TFP complexes exhibited pH-responsive interactions, enabling stable HIPPE formation.
- Optimized HIPPEs (neutral pH, 0.5% TFP) showed enhanced stability, viscoelasticity, and shear-thinning behavior.
- Andr-loaded HIPPEs demonstrated superior protection against UV, heat, and storage, with improved bioaccessibility.
- HIPPEs exhibited excellent 3D printability with high shape fidelity and mechanical resilience.
Conclusions:
- SPI/TFP complexes effectively stabilize HIPPEs for enhanced nutraceutical delivery.
- These HIPPEs offer superior protection, controlled release, and bioaccessibility of bioactive compounds.
- The developed system shows significant potential for customizable 3D-printed functional foods and advanced nutraceutical applications.
