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Related Concept Videos

Applications of IR Spectroscopy: Overview01:11

Applications of IR Spectroscopy: Overview

2.0K
The non-destructive nature and ability to provide valuable chemical information make IR spectroscopy a versatile technique with broad applications in various scientific and industrial fields. IR spectroscopy is commonly used to identify and characterize organic and inorganic compounds. It provides information about the functional groups present in a molecule and the bonding between atoms. This helps in the structural elucidation of compounds during organic synthesis, pharmaceutical research,...
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Infrared (IR) Spectroscopy: Overview01:09

Infrared (IR) Spectroscopy: Overview

4.6K
When electromagnetic radiation passes through a material, atoms or molecules transition from a lower to a higher energy state by absorbing radiation corresponding to the energy difference between the two states. The absorption of infrared (IR) radiation causes transitions between vibrational energy levels in a molecule. Therefore, IR spectroscopy is a useful analytical tool for determining the molecular structure of molecules.
Different compounds display unique properties due to their...
4.6K
IR Spectrometers01:25

IR Spectrometers

2.3K
There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...
2.3K
IR Frequency Region: Fingerprint Region01:03

IR Frequency Region: Fingerprint Region

1.8K
IR spectra are divided into two main regions: the diagnostic region and the fingerprint region. The diagnostic region of the spectrum lies above 1500 cm−1. The absorptions resulting from single-bond vibrations of the N–H, C–H, and O–H stretch at higher wavenumbers and appear on the left side of the spectrum. The stretching absorptions of the C≡C and C≡N occur between 2100–2300 cm−1. In contrast, those arising from stretching absorptions of the...
1.8K
IR and UV–Vis Spectroscopy of Aldehydes and Ketones01:29

IR and UV–Vis Spectroscopy of Aldehydes and Ketones

7.3K
Infrared spectroscopy, also known as vibrational spectroscopy, is mainly used to determine the types of bonds and functional groups in molecules. In aldehydes and ketones, the carbonyl (C=O) bond shows an absorption around 1710 cm-1. The C=O bond vibration of an aldehyde occurs at lower frequencies than that of a ketone. In addition to the C=O absorption in an aldehyde, the aldehydic C–H bond also gives two peaks in the 2700–2800 cm-1 range. This absorption, coupled with the...
7.3K
IR Spectrum01:19

IR Spectrum

2.0K
When infrared (IR) radiation passes through a molecule, the bonds stretch or bend by absorbing the radiation. This absorption creates the molecule's absorption spectrum, which is the plot of its percentage transmittance versus wavenumber.
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
2.0K

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High-definition Fourier Transform Infrared FT-IR Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology
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A software framework for infrared spectral analysis in harm reduction drug checking.

Lea Gozdzialski1, Oscar Sandford1, Zoe Riell1

  • 1Department of Chemistry, University of Victoria, Victoria, British Columbia, Canada.

The American Journal of Drug and Alcohol Abuse
|October 29, 2025
PubMed
Summary
This summary is machine-generated.

A new software framework for drug checking significantly expanded access to this harm reduction intervention. The technology lowers technical barriers, enabling more people who use drugs to receive crucial safety information.

Keywords:
Drug checkingharm reductioninfrared absorption spectroscopyoverdose preventionpoint-of-care analysis

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Area of Science:

  • Analytical Chemistry
  • Public Health Technology
  • Harm Reduction Interventions

Background:

  • Drug checking is a vital harm reduction strategy using chemical analysis to identify illicit drug compositions.
  • Expanding drug checking services is crucial for overdose prevention among at-risk populations.
  • Technical challenges with existing drug checking software limit service accessibility.

Purpose of the Study:

  • To develop and deploy a user-friendly, custom FTIR-based software framework for drug checking.
  • To create a scalable technological infrastructure supporting expanded drug checking services.
  • To improve data accessibility for both clients and public health stakeholders.

Main Methods:

  • Development of a kiosk application integrated with a spectrometer for data collection.
  • Implementation of a centralized database for spectral and survey data storage.
  • Creation of an analysis suite with libraries and tools for spectral interpretation.
  • Online accessibility for individual results and internal dashboards for aggregated data analysis.
  • Generation of tailored public-facing reports for community dissemination.

Main Results:

  • Successful deployment of the software framework across 6 remote service sites by 2024.
  • Analysis of 2673 drug samples for 1926 clients between May 2022 and December 2024.
  • Hundreds of clients accessed drug checking services for the first time.
  • Established systems for generating weekly and monthly aggregate drug data reports.

Conclusions:

  • The developed software framework successfully reduced technical barriers to drug checking.
  • Enhanced service access and provided real-time, actionable data to communities and public health officials.
  • This technological advancement is critical for sustaining and expanding essential drug checking initiatives.