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Updated: Jan 13, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
Cryptogenic Sensory Polyneuropathy and Metabolic Syndrome
Mamatha Pasnoor1, Mazen M Dimachkie2, Richard J Barohn3
1Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
None:
This article reviews the epidemiology and clinical characteristics necessary to make the diagnosis of cryptogenic sensory polyneuropathy (CSPN). This article also discusses the metabolic syndrome and other possible etiologies of neuropathy that need to be excluded before considering the diagnosis of CSPN. Most of the diagnostic testing performed for autoimmune neuropathies and hereditary neuropathies are not necessary to make the diagnosis. Treatment is mostly symptomatic and autoimmune therapies do not have any role in the management of CSPN patients.
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