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Updated: Jan 13, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
Chronic Inflammatory Demyelinating Polyneuropathy and Variants
Amro M Stino1, Richard J Barohn2, Jonathan S Katz3
1Department of Neurology, University of Michigan, F2647 UH South, SPC 5223, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.
None:
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the prototypic chronic inflammatory polyneuropathy, characterized by well-defined clinical and electrodiagnostic criteria, despite the absence of biomarkers or full understanding of disease pathogenesis. It has both a typical form and 5 variants. IVIG remains the treatment of choice for induction or maintenance of remission, although corticosteroids, plasma exchange, and most recently, efgartigimod, demonstrate therapeutic efficacy. Subcutaneous immunoglobulin is indicated only as maintenance therapy. Validated outcome measures exist to track disability, strength, and quality of life and should be routinely employed in clinical practice.
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