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Updated: Jun 26, 2026

Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot Blot Assays
Published on: April 4, 2011
On target: antibodies against the neuraminidase active site
Pradeepa Pushparaj1, Gunilla B Karlsson Hedestam1
1Department of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Abstract:
While often overlooked in studies of influenza antibody responses, the virally encoded neuraminidase (NA) is emerging as an attractive vaccine target due to its comparably high sequence conservation. Recent studies by Jo et al., Lederhofer et al., and Lv et al. reveal a common theme of receptor mimicry mediated by structurally convergent antibodies.
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