Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cognitive Functioning of Low-Grade Glioma Patients with and Without Adjuvant Treatment Before and One Year After Tumor Resection.

Cancers·2026
Same author

Distinct molecular subgroups in pediatric and young-onset meningiomas require age-adapted risk stratification.

Nature communications·2026
Same author

Light on broken networks: Resting-state fNIRS as a tool for connectivity mapping.

NeuroImage·2026
Same author

Exploring brain-glioma interaction: Effect of neuroligin-3 expression on neurocognitive functioning is independent from epilepsy.

Neuro-oncology advances·2026
Same author

Digital MULTIMAP: a standardization of objects and actions naming task in a french population.

Acta neurochirurgica·2026
Same author

Assessing radiological response of IDH-mutated glioma to vorasidenib by tumor diameter slopes: a series of 8 cases.

Acta neurochirurgica·2026

Related Experiment Video

Updated: Jan 12, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.3K

Monitoring of Executive Functions During Awake Glioma Surgery: A Standardized Multicenter Protocol.

Maud J F Landers1, Bart Brouwers1, Anne M Weggelaar2

  • 1Department of Neurosurgery, Elisabeth-Tweesteden Hospital Tilburg, The Netherlands.

Neurosurgery Practice
|October 30, 2025
PubMed
Summary

This study investigates a standardized protocol for monitoring executive functions during awake glioma surgery. The goal is to identify white matter tracts involved in executive functions for improved patient outcomes.

Keywords:
Awake neurosurgeryExecutive functions

More Related Videos

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.5K
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

9.5K

Related Experiment Videos

Last Updated: Jan 12, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.3K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.5K
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

9.5K

Area of Science:

  • Neurosurgery
  • Cognitive Neuroscience
  • Clinical Research

Background:

  • Standardized clinical mapping protocols for monitoring executive functions during awake glioma surgery are lacking.
  • A pilot study developed a feasible standardized monitoring protocol and demonstrated data pooling capabilities.
  • Current fragmentation in the field hinders the generation of reproducible, high-quality datasets for cognitive mapping.

Purpose of the Study:

  • To investigate the efficacy of a standardized protocol in identifying white matter tracts involved in executive functions during awake glioma surgery.
  • To determine if executive functions can be effectively monitored using a standardized protocol across multiple neurosurgical centers.
  • To establish a validated, uniform method for collecting intraoperative findings on executive function mapping.

Main Methods:

  • Prospective, clinical observational multicenter study.
  • Data collection from adult patients undergoing awake primary glioma surgery across multiple neurosurgical departments.
  • Standardized monitoring of executive functions using uniform tasks for specific white matter tracts (frontal aslant tract, superior longitudinal fasciculus I/II, arcuate fasciculus, inferior fronto-occipital fasciculus) pre-, intra-, and post-operatively.

Main Results:

  • The study protocol is designed to collect standardized data to identify white matter tracts associated with executive functions.
  • The primary outcome will be the successful identification of these tracts using the standardized protocol.
  • Data analysis will clarify the clinical relevance of specific white matter pathways in executive functions.

Conclusions:

  • This study is a crucial step towards a validated, uniform approach for intraoperative executive function mapping.
  • The generation of high-quality datasets is essential for advancing the scientific basis of monitoring white matter pathways.
  • Despite inherent limitations of multicenter observational studies, the findings will contribute to improved surgical precision and patient care.