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Bonding of Hydrogel to Biometal Surfaces: Principles, Methods and Applications
Yujie Zhou1, Luyao Zhang1, Shufei Liu1
1Department of Biomedical Engineering Research Center for Nano-Biomaterials and Regenerative Medicine College of Biomedical Engineering Taiyuan University of Technology Taiyuan P. R. China.
Exploration (Beijing, China)
|October 30, 2025
Summary
Modifying metal surfaces with hydrogel coatings improves biocompatibility for implants. This review covers methods for strong biometal-hydrogel bonding to prevent corrosion and inflammation.
Area of Science:
- Biomaterials Science
- Surface Chemistry
- Medical Device Engineering
Background:
- Biometal implants often face challenges like corrosion and inflammation.
- Hydrogels are favored for their biocompatibility, hydrophilicity, and biomechanical properties.
- Functionalized hydrogel coatings can mitigate complications associated with implanted metals.
Purpose of the Study:
- To review methods for achieving robust bonding between hydrogels and biometals.
- To explore surface pretreatment techniques for biometals.
- To summarize bonding strategies and applications of hydrogel coatings on biometals.
Main Methods:
- Literature review focusing on biometal surface modification.
- Analysis of various biometal-hydrogel interface bonding techniques.
- Examination of hydrogel coating applications in clinical settings.
Main Results:
- Biometal surface pretreatment is crucial for effective hydrogel adhesion.
- Multiple bonding strategies exist, each with specific advantages.
- Hydrogel coatings significantly enhance the performance and longevity of biometal implants.
Conclusions:
- Strong biometal-hydrogel bonding is essential for advanced biomedical applications.
- Surface pretreatment and optimized bonding methods are key to successful hydrogel coating.
- Hydrogel coatings represent a promising strategy to improve the clinical outcomes of biometal implants.
