Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

385
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
385
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

456
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
456
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

237
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
237
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

363
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
363

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postmyocardial infarction ventricular septal defect outcomes: Partial versus full presurgical hemodynamic support.

JTCVS open·2026
Same author

Impact of aortic root surgery during transcatheter aortic valve explant.

JTCVS structural and endovascular·2026
Same author

Bioprosthetic versus mechanical surgical aortic valve replacement in patients ≥65 years of age.

JTCVS open·2026
Same author

Temporizing Balloon Aortic Valvuloplasty Before Transcatheter Aortic Valve Replacement in Decompensated Severe Aortic Stenosis.

The American journal of cardiology·2026
Same author

Aortic root replacement after repaired congenital conotruncal defects: A surgical challenge.

JTCVS open·2026
Same author

Transcatheter vs Surgical Tricuspid Valve Repair: An Analysis of Medicare Beneficiaries.

The Annals of thoracic surgery·2026

Related Experiment Video

Updated: Jan 12, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.6K

Aortic Valve Repair for Severe Commissural Leaflet Defects Using Aortic Wall Patches.

Alexander P Nissen1, Melissa M Levack2, Vinay Badhwar3

  • 1Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.

Annals of Thoracic Surgery Short Reports
|October 30, 2025
PubMed
Summary

A novel aortic wall patch technique effectively repaired severe aortic valve leaflet deficiencies in a patient, restoring normal function and avoiding prosthetic valve replacement. This method offers a promising solution for complex aortic insufficiency cases.

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies
06:56

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Published on: August 25, 2023

1.6K

Related Experiment Videos

Last Updated: Jan 12, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.6K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies
06:56

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Published on: August 25, 2023

1.6K

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Valve Repair
  • Aortic Valve Disease

Background:

  • Annular dilatation and leaflet defects are common in aortic insufficiency, often requiring valve repair or replacement.
  • Inadequate leaflet tissue during planned repair can unexpectedly necessitate prosthetic valve replacement.
  • A need exists for effective repair methods for severe leaflet deficiencies in aortic valve insufficiency.

Purpose of the Study:

  • To present a novel surgical technique for repairing severe aortic valve leaflet deficiencies.
  • To evaluate the efficacy of using an autologous aortic wall patch for leaflet reconstruction.

Main Methods:

  • A major leaflet defect in a patient with aortic insufficiency was reconstructed using an autologous aortic wall patch.
  • The aortic wall strip was sutured to the valve annulus, with intima facing coaptation.
  • Leaflet free-edge length was adjusted to match normal leaflets after geometric annuloplasty.

Main Results:

  • A patient with grade 4 preoperative aortic insufficiency experienced a complete resolution of insufficiency after repair with an aortic wall patch.
  • The patient demonstrated excellent echocardiographic parameters at 1 year postoperatively.
  • This technique successfully addressed severe leaflet deficiency, avoiding prosthetic valve replacement.

Conclusions:

  • Autologous aortic wall patches are an effective leaflet substitute for managing severe leaflet deficiencies during aortic valve repair.
  • This technique provides a viable alternative to prosthetic valve replacement in complex aortic insufficiency cases.
  • The presented method offers a stable and durable solution for aortic valve leaflet reconstruction.