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Mandibular Metastasis From Colon Cancer Presenting as Jaw Pain
Osama Faridi1, Hajra Jamil2, Faisal Mehmood3
1Medicine, Midwestern University Arizona College of Osteopathic Medicine, Glendale, USA.
Cureus
|October 30, 2025
Summary
A rare case of colorectal cancer (CRC) metastasizing to the jaw highlights the importance of recognizing atypical symptoms. Early diagnosis and systemic chemotherapy are crucial for managing this rare oral metastasis and improving patient outcomes.
Area of Science:
- Oncology
- Gastroenterology
- Oral Surgery
Background:
- Colorectal cancer (CRC) commonly metastasizes to the liver, lungs, peritoneum, and lymph nodes.
- Osseous metastases from CRC are uncommon, with mandibular involvement being exceedingly rare.
- Atypical presentations of CRC, especially with metastatic disease, necessitate a broad differential diagnosis.

