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In vitro Assessment of a Deep Learning-Based System for Computer-Aided Diagnosis and Treatment Planning in
Amit Anthony1, Maheswari Eluru2, Rahul Sharma3
1Department of Orthodontics and Dentofacial Orthopaedics, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|October 30, 2025
Summary
Artificial intelligence (AI) shows promise in automating orthodontic diagnosis and treatment planning. A deep learning system achieved over 90% accuracy in identifying malocclusions, suggesting AI
Area of Science:
- Orthodontics
- Artificial Intelligence
- Medical Imaging
Background:
- Automating orthodontic diagnosis and treatment planning can enhance efficiency and accuracy.
- Digital orthodontic models are increasingly utilized in clinical practice.
Purpose of the Study:
- To evaluate the efficacy of a deep learning-based artificial intelligence (AI) system for computer-aided orthodontic diagnosis and treatment planning.
- To assess the performance of AI in analyzing digital orthodontic models.
Main Methods:
- A deep learning AI system was developed and trained on 100 three-dimensional digital orthodontic models.
- The AI system was tasked with recognizing malocclusions and generating treatment recommendations.
- AI-generated results were compared against evaluations by qualified orthodontists.
Main Results:
- The AI system demonstrated high accuracy in malocclusion categorization.
- Sensitivity and specificity for malocclusion identification exceeded 90% in most cases.
- AI performance was comparable to that of experienced orthodontists.
Conclusions:
- The findings support the potential of AI in automating orthodontic diagnosis and treatment planning.
- Further clinical validation is necessary to confirm the efficacy of AI in orthodontics.
- AI holds promise for improving efficiency and accuracy in orthodontic workflows.

