Survey on the Public Opinion and Attitudes Toward Uterus Transplantation in Hungary

Uterus transplantation (UTx) is a novel and clinically successful treatment option for patients with absolute uterine factor infertility (AUFI) who wish to achieve biological motherhood. Although over 100 UTx procedures have been performed at 20 centers worldwide in the past decade, the procedure remains relatively unknown-even among healthcare professionals. This study aimed to assess public opinion regarding UTx and to identify knowledge gaps in the Hungarian population's awareness and perception of the procedure.

This prospective study was conducted between December 18, 2024, and January 5, 2025, via an online survey involving 2896 participants. A final representative sample of 1500 individuals was selected using an iterative mathematical weighting method, adjusted to the 2022 Hungarian census data. The sample was representative of the Hungarian internet-using population aged 18-70 years in terms of age, gender, education level, and place of residence. The 24-item questionnaire assessed participants' views on organ donation, transplantation, infertility, surrogacy, and UTx.

Most respondents (77%; 1155/1500) supported UTx (strongly agree: 44%, 660/1500; agree: 33%, 495/1500). Among participants personally affected by fertility issues, 84% (152/181) expressed support, with 51% (92/181) strongly agreeing that UTx should be offered. Only 4% of the total samples opposed the procedure. Notably, just 15% of respondents were previously aware that UTx had been performed internationally.

This online survey demonstrates substantial public approval for UTx in Hungary, particularly among individuals affected by infertility. However, public awareness of the procedure remains limited, indicating a need for increased education and communication to improve general knowledge on the topic.