Related Experiment Video
Updated: Jan 6, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Acute Left Ventricular Dysfunction After Mitral Transcatheter Edge-to-Edge Repair
Luca Raone1, Marco Ferlini2, Francesco Maria Sparasci1
1Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Background:
Mitral transcatheter edge-to-edge repair (M-TEER) is an established treatment for severe mitral regurgitation. However, acute left ventricular (LV) dysfunction may complicate the procedure through mechanisms with distinct implications.
Case Summary:
An 81-year-old man with severe primary mitral regurgitation underwent elective M-TEER. Immediately after clip deployment, he developed acute LV dysfunction, initially managed as afterload mismatch (AM) with vasodilators. The clinical evolution was associated with apical ballooning on echocardiography, with electrocardiographic changes and troponin elevation without obstructive coronary disease, supporting Takotsubo syndrome (TTS). The patient remained stable, and LV function fully recovered within 1 week.
Discussion:
This case illustrates the difficulty of distinguishing AM from TTS after M-TEER, 2 entities with overlapping features but different prognostic and therapeutic implications.
Take-Home Messages:
Acute LV dysfunction after M-TEER should not be automatically attributed to AM. TTS should be considered, and the integration of clinical, echocardiographic, and electrocardiographic findings is essential to management.
More Related Videos
08:19Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
Published on: July 12, 2022
07:41Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Regurgitation I: Introduction
Mitral Regurgitation III: Medical Management
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Cardiomyopathy II: Dilated Cardiomyopathy