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Updated: Jan 12, 2026

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
Oncocytic lipoadenoma of the submandibular gland case report
Mina A Beshy1, Fayssal Alqudrah1, Isago Jerrett2
1Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ, 08901, United States of America.
Introduction:
Oncocytic lipoadenomas represent a rare, benign variant of salivary gland tumors (SGT). The parotid gland is the most common location for these tumors, accounting for 85 % of cases, followed by the submandibular gland. There have only been 7 reported cases of submandibular gland oncocytic lipoadenomas documented to date.
Main Concerns:
Herein, we present a case of an asymptomatic 47-year-old female with no significant past medical history who was incidentally diagnosed with a mass of the submandibular gland. We proceeded with complete surgical excision of the left submandibular gland, along with a neck dissection to ensure the removal of any potentially neoplastic tissue.
Primary Diagnosis And Outcomes:
Histopathologic analysis of the excised mass revealed lobulated adipocytic tissue intermixed with small, scattered foci of salivary gland tissue, and several areas of oncocytic glandular tissue surrounded by patchy chronic inflammation, consistent with previously reported findings of oncocytic lipoadenomas.
Conclusions:
This case underscores the rarity of this benign entity and highlights its inclusion in the differential diagnosis of salivary gland masses. Furthermore, it emphasizes the importance of diagnostic imaging and histopathologic analysis following core needle biopsy, as biopsy alone may not provide sufficient diagnostic clarity.

