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Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy
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Precision Medicine in Thoracic Surgery: Esophageal Cancer
Christian C Cullen1, Fatima G Wilder2, Rian M Hasson2
1Department of Surgery, Brigham and Women's Hospital, Mass General Brigham, Boston, MA, USA.
Abstract:
Esophageal cancer, ranking 18th in incidence and 14th in mortality in the United States, has a low 5-year survival rate of around 20%. The 2 main histologic subtypes are esophageal adenocarcinoma, prevalent in Western countries and linked to obesity and gastroesophageal reflux disease, and esophageal squamous cell carcinoma, more common worldwide and associated with lifestyle risk factors like tobacco and alcohol. Accurate staging using endoscopic ultrasound, computed tomography, and PET scans guides treatment decisions, with multimodal approaches including surgery, chemoradiotherapy, and systemic therapies. Ongoing research into molecular targets and immunotherapies promises further improvements in management and survival for esophageal cancer patients.
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