Unusual co-occurrence of cheilitis granulomatosa and plasma cell gingivitis: A case report

Cheilitis granulomatosa (CG) and plasma cell gingivitis (PCG) are uncommon inflammatory conditions affecting the oral regions. CG manifests as chronic lip swelling with granulomatous inflammation, while PCG presents as erythematous gingiva or gingival enlargement linked to hypersensitivity reactions. Their simultaneous occurrence is exceedingly rare, posing diagnostic and therapeutic challenges.

A 32-year-old woman presented with recurrent upper lip swelling and gingival enlargement. Clinical examination revealed erythematous gingiva with a cobblestone texture and angular cheilitis. Biopsies confirmed orofacial granulomatosis with epithelioid granulomas and PCG with plasma cell infiltration. Management consists of diet modification and periodontal intervention. Postoperative outcomes demonstrated significant improvement, and allergen elimination strategies were implemented to reduce recurrence.

At 9 months of follow-up of the patient, there was significant improvement in signs and symptoms with no signs of recurrence.

This case highlights the rare co-existence of CG and PCG, emphasizing the need for a comprehensive diagnostic approach to exclude systemic causes. Successful management requires pharmacological treatment, surgical interventions, and dietary modifications. Long-term follow-up is essential to monitor recurrences and maintain clinical stability.

Because of the rare co-occurrence of cheilitis granulomatosis (CG) and plasma cell gingivitis (PCG), which creates unique diagnostic and therapeutic hurdles, this case offers new information. Additionally, it presents an effective treatment plan that concurrently addresses both problems. A comprehensive strategy is necessary for the successful management of PCG and CG. Systemic disorders must be ruled out since they might exhibit similar symptoms. Dietary changes, nonsurgical, and surgical periodontal therapy are all part of the therapy plan. In order to avoid recurrence and guarantee a long-lasting recovery, long-term monitoring and regular elimination of allergens and irritants are essential. The possibility of the problem recurring is one of the main obstacles to this case's success. Reducing the chance of recurrence requires adhering to dietary changes and getting rid of allergens. Additionally, before initiating any kind of treatment, systemic disorders must be ruled out.

Cheilitis granulomatosa (CG) and plasma cell gingivitis (PCG) are two uncommon conditions that affect the oral cavity. In this case report, a 32-year-old female patient presented with swelling of the lip and enlargement of the gums. There was a presence of cracks at the corners of the mouth, along with redness of gums with uneven texture. Investigations were done to rule out other possible causes of the same. Histopathological analysis of the lip and gums confirmed the diagnosis of CG and PCG. The patient was treated with non-surgical and surgical periodontal therapy, along with education to avoid possible allergens in her diet. Symptomatic relief occurred after the therapy. The patient was followed up for up to 9 months, and there were no signs of recurrence of the condition.