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A review on impact of adipocytokines in post postmenopausal women
Eslavath Sukanya1, Ponnazhagan2, Veluri Ganesh3
1Department of Biochemistry, Sri Chamundeshwari Medical College, Hospital & Research Institute, Ramanagara, Channapatna, Karnataka, India.
Abstract:
Obesity in postmenopausal women is a major global health concern due to hormonal and metabolic changes. This review explores the roles of ghrelin, leptin, adiponectin, insulin, AMPK, and vitamin D in energy regulation and weight fluctuation. Estrogen decline post-menopause alters metabolic balance, contributing to fat accumulation and insulin resistance. Reduced adiponectin and disrupted leptin-ghrelin signalling are linked with increased body mass index. Vitamin D sufficiency, alongside lifestyle changes, may support weight management in this population.
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