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Pyrene/Methoxy-Functionalized Covalent-Organic Framework as an OFF-ON Fluorescence Sensing Probe for
Guangrao Chen1, Lin Cai1, Wen Hao1
1State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
Analytical Chemistry
|October 31, 2025
Summary
A novel covalent-organic framework (COF) enables sensitive fluorescence detection of the insecticide cartap. This method offers a rapid and visual approach for monitoring cartap residues in food safety applications.
Area of Science:
- Materials Science
- Analytical Chemistry
- Environmental Science
Background:
- Cartap insecticide residues pose risks to aquatic ecosystems, agricultural product safety, and human health.
- Developing sensitive and selective detection methods for cartap is crucial for food safety and environmental monitoring.
Purpose of the Study:
- To construct a covalent-organic framework (COF), Py-DMTA-COF, for the fluorescence (FL) and visual detection of cartap.
- To investigate the mechanism of cartap detection using the synthesized COF.
Main Methods:
- Synthesis of Py-DMTA-COF via Schiff base reaction between TAPPy and DMTA.
- Fluorescence spectroscopy for detecting cartap, utilizing photoinduced electron transfer (PET) and interlayer interactions.
- Smartphone-assisted visual detection platform for quantitative analysis.
Main Results:
- Py-DMTA-COF exhibited fluorescence quenching (FL-OFF) due to PET and strong interlayer interactions.
- Cartap induced fluorescence recovery (FL-ON) by blocking PET and weakening interlayer interactions.
- Achieved a low limit of detection (LOD) of 0.11 ng mL⁻¹ for cartap using FL spectroscopy.
- Smartphone-based visual detection demonstrated a linear range of 0.05–16 μg mL⁻¹ with an LOD of 0.0138 μg mL⁻¹.
Conclusions:
- The developed Py-DMTA-COF is a highly sensitive fluorescent sensor for cartap detection.
- The smartphone-assisted visual platform offers a portable and efficient method for on-site cartap monitoring.
- This approach holds significant potential for high-precision detection of hazardous substances in food.
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