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Updated: Jan 12, 2026
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Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
Published on: February 9, 2022
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Maximal dynamic inspiratory pressure: S-Index prediction values and diagnosis accuracy
Vitor Costa Souza1, Maria Fernanda Lima Souza Saldanha1, Eloara Vieira Machado Ferreira1
1. Função Pulmonar e Fisiologia Clínica do Exercício, Divisão de Pneumologia, Universidade Federal de São Paulo, São Paulo (SP) Brasil.
Summary
This study establishes reference values for the strength index (S-Index) to aid in diagnosing inspiratory muscle weakness. The S-Index shows potential for ruling out weakness, especially when below normal limits.
Area of Science:
- Respiratory Physiology
- Pulmonary Function Testing
Background:
- Maximal dynamic inspiratory pressure (MIP) is crucial for assessing respiratory muscle function.
- Clinical demand for reliable diagnostic tools for inspiratory muscle strength is increasing.
Purpose of the Study:
- To establish reference values and prediction equations for the strength index (S-Index).
- To explore the S-Index's clinical application in diagnosing inspiratory muscle weakness.
Main Methods:
- Prospective study of 120 healthy adults (18-80 years).
- Measured S-Index and MIP, analyzing differences.
- Developed a multiple linear regression model for S-Index prediction.
- Validated the model using COVID-19 survivors.
Main Results:
- S-Index correlated with FEV1 and FVC.
- Sex, age, weight, and height explained 62% of S-Index variation.
- Prediction equation differentiated COVID-19 survivors based on MIP.
- S-Index showed potential for ruling out, not confirming, inspiratory muscle weakness.
Conclusions:
- First reference equations for S-Index in a healthy Brazilian adult population.
- S-Index explored as an adjunct index for evaluating inspiratory muscle strength.
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