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Updated: Jan 12, 2026

Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells
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TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells

Hoyoung Lee1, So-Young Kim2, Sang-Hoon Kim1

  • 1Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; The Center for Viral Immunology, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon 34126, Republic of Korea.

Immunity
|November 1, 2025
PubMed

Keywords:
Ca(2+)–calcineurin signalingIL-15NFATc1TCRbystander activation

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