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Updated: Jan 12, 2026

Stimulation of Notch Signaling in Mouse Osteoclast Precursors
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Stimulation of Notch Signaling in Mouse Osteoclast Precursors

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Osteoclast-Derived Exosomes Promote MRONJ via the VEGFR2-Caspase9 and Notch1-Hes1/Hey Signaling Pathways

Kun Zhang1,2, Jiankang Zhang1, Qizhang Wang1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Oral Diseases
|November 2, 2025
PubMed
Abstract

Keywords:
bisphosphonatesexosomesmedication‐related osteonecrosis of the jawosteoclasts

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